Information in the news releases is current on the date of the announcement, but is subject to change without prior notice. |
| 2006 Release |
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| November 21, 2006 |
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Eisai Announces Establishment of New Pharmaceuticals Marketing Subsidiary in Portugal

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| November 20, 2006 |
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Eisai Recieves Positive Opinion for Inovelon Marketing Authorization from European Committee for Medicinal Products for Human Use (CHMP)

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| October 31, 2006 |
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Eisai Launches New Rx-to-OTC Switch Product Higuard for Allergy-related Rhinitis and Skin Problems

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| October 30, 2006 |
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Notice Regarding Revision of the Annual Business Forecast and Year-end Dividend Forecast by Subsidiary

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| October 26, 2006 |
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Eisai Announces Completion of Acquisition of Four Oncology-Related Products from Ligand

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| October 19, 2006 |
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Sanko Junyaku, Eisai, and FUJIREBIO Sign Joint Research Agreement for Development of a New KL-6 Test Kit (supplementary diagnostic marker for interstitial pneumonia) compatible with LUMIPULSE (automatic chemiluminescent enzyme immunoassay system)

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| October 19, 2006 |
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Notice Regarding Revision of the Semiannual Business Forecast by Subsidiary

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| October 14, 2006 |
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U.S. FDA Approves Aricept For Treatment of Severe Alzheimer's Disease

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| October 9, 2006 |
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Eisai Receives Decisions of Summary Judgment Motion in US Legal Action Over Aciphex ANDA Filing

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| October 2, 2006 |
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Eisai's research subsidiary “KAN Research Institute” launches research operations in The Kobe Medical Industry Development Project Site

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| September 27, 2006 |
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Eisai's Lawsuit against three Japanese Generic drug manufacturers/distributors regarding the sales of Selbex based on the Japanese Unfair Competition Prevention Law dismissed by Court

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| September 8, 2006 |
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Eisai Acquires Four Oncology-Related Products from Ligand

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| August 30, 2006 |
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Notice Concerning the Result of the Company's Own Share Acquisition through ToSTNet-2

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| August 29, 2006 |
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Notice Concerning Acquisition of the Company's Own Shares through ToSTNet-2

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| August 4, 2006 |
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Eisai Commences U.S. Legal Action over Aricept ODT ANDA Filing

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| July 31, 2006 |
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Eisai Starts Marketing Severe Chronic Pain Agent Prialt in the UK and Germany

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| July 31, 2006 |
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Continuation of Policy for Protection of the Company's Corporate Value and Common Interests of Shareholders

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| July 31, 2006 |
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Notice Concerning Acquisition of the Company's Own Shares

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| July 27, 2006 |
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Co-development and Distribution Agreement on treatment for pancreatic exocrine insufficiency (SA-001) in Japan concluded

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| July 12, 2006 |
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Eisai and Teva Mutually Agree To End Collaboration Agreement for Rasagiline

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| July 10, 2006 |
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Notice on Stock Options (New Share Subscription Rights) Including the Amount Paid In Upon the Exercise of Stock Options

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| July 4, 2006 |
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Pharmaceutical Marketing Subsidiary in Singapore Launches Operations

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| June 29, 2006 |
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Eisai Licenses Selective Estrogen Receptor Modulators (SERMs) to Radius

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| June 23, 2006 |
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Notice on Allotment of Stock Options (New Share Subscription Rights)

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| May 19, 2006 |
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Notice Concerning Dissolution of Subsidiary

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| May 16, 2006 |
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Notice on Partial Amendments to the Articles of Incorporation

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| May 16, 2006 |
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Notice on New Stock Issuance in the Form of Stock Options

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| May 16, 2006 |
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Eisai Files Application with the MHRA for New Aricept Indication: Severe Alzheimer's Disease

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| May 10, 2006 |
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Eisai and Nitto Denko Sign a Joint Development Agreement on a Transdermal Patch Formulation of Aricept

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| May 9, 2006 |
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Eisai will initiate first clinical study for E2012, a potential new treatment for Alzheimer's Disease

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| April 21, 2006 |
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Personal Information Documentation Loss Release

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| April 17, 2006 |
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Dainippon Sumitomo Pharma and Eisai Signed Licensing Agreement for "Gasmotin ", a Gastroprokinetic Agent, for Countries in Asia including ASEAN Members

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| March 31, 2006 |
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Asahi Kasei Pharma and Eisai sign sales promotion agreement for Eril in China

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| March 30, 2006 |
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Eisai and DNAVEC Sign an Agreement on Drug Discovery Research for Vaccine Therapy for Alzheimer's Disease

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| March 29, 2006 |
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Notice of Shelf Registration for Stock Options

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| March 27, 2006 |
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Eisai Applies for a New Indication of Non-Erosive Gastro-Esophageal Reflux Disease for Pariet a Proton Pump Inhibitor, in Japan

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| March 16, 2006 |
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Eisai Reports Results from Latest Donepezil Study in Vascular Dementia

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| February 28, 2006 |
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Policy for Protection of the Company's Corporate Value and Common Interests of Shareholders

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| February 28, 2006 |
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Announcement of the 5th Mid-term Strategic Plan

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| February 24, 2006 |
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Notice Concerning the Split-off of Management Function of the R&D Division and Other Relevant Function of Eisai Co., Ltd.

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| February 14, 2006 |
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FDA Accepts Eisai's sNDA Application for Aricept In the Treatment of Severe Alzheimer's Disease

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| February 9, 2006 |
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Eisai Agrees To Acquire Severe Chronic Pain Agent Prialt For Europe From Elan

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| February 2, 2006 |
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Notice Concerning Revision of Year End Dividend Forecast For Fiscal Year Period (94th Company Fiscal Period) Ending March 2006

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| January 24, 2006 |
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Eisai establishes a European strategic business hub in the U.K.

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| January 13, 2006 |
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Legal Action taken against Generic Products of Eisai's Selbex Capsule 50mg based on the Japanese Unfair Competition Prevention Law in the Japanese Market

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